Keep it in One Application
In most cases, it’s best to keep your company’s work in a single QuickBase application. That’s because tables often relate to each other. For example, if you have one application for Order Entry and another for Customer Satisfaction, they are both going to use your Customer List, your Employee List, and probably other tables too. You don’t want to have two Customer lists so that means that one application will need to hold the Customer list, and the other will have to use a cross-application relationship to see it. Cross-application relationships are OK, but they have some limits. Better to keep it all in one application.
Of course, there are exceptions to this. If your applications are owned by different people, or they just get big and un-manageable, it’s best to separate them. But don’t do it unless you have a good reason.